PROSITE entry PS51829

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS51829
Entry name [info]	P_HOMO_B
Accession [info]	PS51829
Entry type [info]	MATRIX
Date [info]	15-MAR-2017 CREATED; 13-FEB-2019 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC51829
Associated ProRule [info]	PRU01173

Name and characterization of the entry

Description [info]

P/Homo B domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=136;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=136;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.4824312; R2=0.0089508; TEXT='-LogE';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=18398.0605469; R2=4.9227300; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=1008; H_SCORE=23360; N_SCORE=11.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=449; H_SCORE=20608; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: M0=-31; D=-150; I=-150; B1=-1000; E1=-1000; MI=-380; MD=-380; IM=-380; DM=-380;

...

                A    C    D    E    F    G    H    I    K    L    M    N    P    Q    R    S    T    V    W    Y
/I:         B1=0; BI=-380; BD=-380;
/M: SY='T';  M=   4, -78, -64, -64, -32,  -3, -40, -46, -61,  -4, -55,  15, -48, -28,   6,   8,  54,  43, -23, -53;
/M: SY='V';  M=  -2, -64, -38, -22, -35,   9, -75, -59,   1, -18, -73,  17,  31,   5, -59,  12, -17,  51, -23, -56;
/M: SY='P';  M=  15, -49, -41, -16, -70, -48, -35, -44, -65, -69, -47, -11, 108, -63, -53, -34, -20, -53,   5, -59;
/M: SY='Q';  M= -21, -84, -23,  51, -53,   4, -58, -79, -21, -47,   2, -28,   3,  80, -14,  14, -26, -65, -34, -25;
/M: SY='Q';  M=  10, -64, -43, -52, -72, -30, -16, -68,  10,  -5, -32, -31,  11,  66,  38, -20,  40, -42, -40, -64;
/I:         I=-17; MI=0; MD=-44; IM=0; DM=-44;
/M: SY='W';  M= -72,   5, -54, -37, -54, -73,  35,   0,   2, -53, -25, -51, -12, -44,  -5,   9,  -7, -53,  75, -52; D=-17;
/I:         I=-17; DM=-44;
/M: SY='C';  M= -44,  86, -61, -59,   3, -50, -64, -23, -77, -12, -55, -81, -45, -16, -58, -27, -10,   0,   1,   8; D=-17;
/I:         I=-17; DM=-44;
/M: SY='C';  M= -27,  36, -40,   7, -36, -18,  -3, -33, -10, -53, -80, -31, -54, -34, -19,  -9,  32,   6, -50,  -9; D=-17;
/I:         I=-17; DM=-44;
/M: SY='S';  M= -14, -37, -53, -12, -47,  -3, -57,   8, -31, -28, -33, -27, -34,  13, -22,  24,  -6,  13, -78,  -3; D=-17;
/I:         I=-17; DM=-44;
/M: SY='P';  M=  -4, -31,   2,   8, -32,  11, -34, -55, -30, -49, -61,  -2,  31, -18,  -6,  19,  14, -49, -73, -21; D=-17;
/I:         I=-17; DM=-44;
/M: SY='S';  M=  -1, -54, -12,  -8, -27, -48, -27,   8, -31, -44, -33, -12, -33, -49, -44,  31,  25,  18, -24,  27; D=-17;
/I:         I=-17; DM=-44;
/M: SY='F';  M= -33, -70,   1, -35,  29,  -6, -44,  11, -27,  -3, -25,  -3,  19,  -7, -14, -10,  21,  -3, -19, -30; D=-17;
/I:         I=-17; DM=-44;
/M: SY='N';  M= -16, -63,  13,  -3,  -7, -20,   7, -36,   3, -24, -28,  42, -21,   4, -29,  23,  26, -40,-112, -20; D=-17;
/I:         I=-17; DM=-44;
/M: SY='N';  M=   1, -45,  17,  16, -39,  -2, -37, -35, -42, -32, -29,  40,  16, -12,  -9, -21,  15,  21, -32, -30; D=-17;
/I:         I=-17; DM=-44;
/M: SY='N';  M= -19, -41,  23, -12, -50, -16,  -3, -50, -34, -34, -30,  48,  46,  16, -37,  12,  26, -13, -11, -40;
/M: SY='Q';  M=   2, -48,  -1,  -7, -24, -25, -17, -10,  19, -20, -25,   3,  31,  44,   4, -11,  22, -29, -52, -39;
/M: SY='D';  M=  11, -32,  26,   6, -72, -27, -38, -27,   1, -27, -62,   1,  20,  -4,  -3,  18,   5,  19, -47,  -9;
/M: SY='I';  M=  11,-104, -50, -37,  -3, -69, -46,  62, -39,  -9, -23, -18,  -7, -31, -20, -30,   8,  23,   5,  10;
/I:         I=-36; MD=-90;
/M: SY='P';  M=  -7, -81, -20, -31, -42, -34, -62,  43, -14, -10, -48, -11,  67, -24, -12,  10,  -9, -30, -31, -21; D=-36;
/I:         I=-36; MD=-90;
/M: SY='P';  M=  -8, -64,  15, -22, -21, -27, -27,  21, -34, -40, -20,  -1,  51,   3,  -5,  17,  14, -13, -29, -18; D=-36;
/I:         I=-36; MD=-90;
/M: SY='D';  M= -11, -44,  51, -24, -83,   0, -34, -34, -28, -63, -44,  43,  29, -10, -11,   9,  15, -35, -18, -24; D=-36;
/I:         I=-36; MI=0; MD=-90; IM=0; DM=-90;
/M: SY='D';  M= -19, -82,  49, -17, -39,  33, -24, -64, -23, -36, -14,  44,  11,  -7,   1,  -3, -22, -24, -67,  -9;
/M: SY='S';  M=   0, -48, -11,  12, -61,  30,   7, -56,  10, -37, -52,  24, -11,   5, -15,  32,  15, -38, -77, -25;
/I:         I=-19; MD=-49;
/M: SY='G';  M= -20, -56, -19, -38, -40,  -3, -27, -40, -36, -40, -51,  -5, -12, -15, -50, -15, -24, -17, -29, -46; D=-19;
/I:         I=-19; MI=0; MD=-49; IM=0; DM=-49;
/M: SY='T';  M=  14, -76, -70,  -5, -71,  19, -36,  -4, -31,  -9, -36, -15,  37, -16, -14,  16,  41, -11,  -9, -74;
/M: SY='V';  M= -11, -78, -47, -56,  -1, -61, -62,  39, -82,  30, -11, -56, -31, -69, -38,   5,  -4,  53, -63, -35;
/M: SY='T';  M= -39, -76, -24,  43, -35, -34, -16, -19, -23, -43, -56,  -3,  -5,  16,   4,  23,  56, -14, -32, -21;
/M: SY='S';  M= -35, -65,   7, -42, -15, -30, -22,  19, -51,   7, -33, -11, -62, -35, -46,  71,  -4,   4,-110, -51;
/M: SY='S';  M= -19,-103, -18,   9, -44, -49, -16,  -2, -34, -23, -32,  10,  38,  12,  -4,  40,  37,  -9,-110, -41;
/M: SY='I';  M= -38,-104, -22, -66,  34, -51, -31,  57, -21,  16,   4, -62, -20, -27, -47, -52,  15,  18,  13,  -2;
/M: SY='T';  M=   0, -59,  14, -15, -55, -47, -28, -51,  -6, -61, -47,  38,   6,   0, -23,  13,  67, -29, -61,   4;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='V';  M=   4, -16, -53, -57,  -9, -42, -73,  31, -88, -28, -31,  -5, -50, -43, -86,  10,   9,  70, -80, -74;
/M: SY='T';  M=  16,  24,  31, -14, -77, -10, -36, -76, -32, -83, -75,  16,  -4, -58, -47,  44,  60, -55,-115, -55;
/I:         I=-17; MD=-42;
/M: SY='G';  M=   0,  17, -45,  -3, -66,  32, -56, -77, -22, -88, -88,-109, -14, -26,  -7, -39, -70, -72,  -8, -81; D=-17;
/I:         I=-17; MI=0; MD=-42; IM=0; DM=-42;
/M: SY='C';  M= -39,  72,  -5, -26, -62, -90, -75, -40, -24, -56, -58, -66,-134, -27, -83,  -2, -44, -60,-143, -65; D=-17;
/I:         I=-17; DM=-42;
/M: SY='D';  M= -20, -28,  10,   4, -55, -55, -28, -93, -52, -42,   8, -37, -75, -41, -16, -14,  -8, -71, -41, -53; D=-17;
/I:         I=-17; DM=-42;
/M: SY='G';  M= -53, -63, -30, -56, -41,  21, -17,  -3, -90,   1, -52, -15, -78, -77, -69, -20, -49, -29,-131, -66; D=-17;
/I:         I=-17; DM=-42;
/M: SY='T';  M= -35, -33,   5,   1, -87, -56, -70, -89, -19, -59, -20, -19, -17,  14, -28,   7,  20, -61,-133, -70; D=-17;
/I:         I=-17; DM=-42;
/M: SY='G';  M= -39, -19,  16,   2, -53,  18, -59, -15, -15, -31, -15,  -5, -19, -27, -34,  -9, -35, -22,-123, -42; D=-17;
/I:         I=-17; DM=-42;
/M: SY='N';  M=   4,  36, -22, -25, -65, -15,  -3, -51, -50, -49, -47,  41, -44, -12, -20,  10,   5, -23, -62, -20; D=-17;
/I:         I=-17; DM=-42;
/M: SY='E';  M=   4, -17,  27,  41, -41,  -9,   7, -87,  -4, -39, -52,  36,  -6,  20,   1,   3,   2, -36, -41, -26;
/M: SY='V';  M= -11, -74,  10, -44,   4,  21, -21,  35, -53,  -6, -24, -17, -14, -35, -45, -14,  -6,  44, -46, -59;
/M: SY='N';  M= -21, -53, -23,  -5,  -4,  16, -14,   2,   6,  -3,   3,  44, -56,  -5,  11,   2,   3,  -6,-107, -36;
/M: SY='Y';  M=   5, -71, -18, -20,   5, -35, -10, -19,  -1, -46, -42, -15, -11, -27,  22,  14,  30, -15, -30,  66;
/M: SY='L';  M= -19, -48, -68, -90, -44, -85,-104,  40, -86,  57, -28, -56,  -7, -58, -96,  -6, -12,  43,-107, -89;
/M: SY='E';  M=  -6,-108, -20,  97, -55, -42, -50, -80, -31, -82, -54, -47, -71,  -7, -30,   1, -10, -63, -71,-101;
/M: SY='H';  M= -11,-108,  22, -44, -43, -36, 115, -54, -36, -79, -57,   1, -52,  -6,  -3,   2,   2, -64,  18,   6;
/M: SY='V';  M=  -4, -99, -50, -91, -51, -81,-111,  33, -90,   5, -33, -83,-108,-104, -95, -29, -36,  86,-113, -92;
/M: SY='Q';  M= -37, -53, -18,  18, -87, -61, -36, -29,  -6, -38, -72,   4, -65,  87,   0,   4,  40,  -8,-109, -43;
/M: SY='V';  M=   7, -15,-111, -90, -52,-100,-109,  25, -88,  31, -40, -86, -67,-104,-106, -45, -42,  79,-112, -91;
/M: SY='T';  M= -23, -64,  -3,   3, -16, -42,  10,  -4,  12, -46, -50,  -3, -82,  -2,  25,   5,  58,  -2,-108,   0;
/M: SY='V';  M= -38,-100, -95,-108,  -5, -62,-108,  33,-106,  39,   1, -90, -87, -71,-107, -66, -39,  75, -45, -65;
/M: SY='D';  M= -33, -72,  60, -23, -67, -53,   2, -82, -27, -78, -99,  56, -98, -22, -19,  31,  53, -58,  35, -62;
/M: SY='I';  M= -15, -62,-113, -97,  -3, -47, -75,  80,-107,  37,  17,-106,-107,-103,-108, -53, -22,  10, -20, -59;
/M: SY='T';  M= -20, -76,  37,  18, -64, -49, -30, -50,  -1, -75, -62,  20, -46,  21,  14,  26,  53, -20,-113, -40;
/I:         I=-12; MI=0; MD=-31; IM=0; DM=-31;
/M: SY='H';  M= -15, -86, -73, -89,  -4, -68, 133,-103, -82, -66, -53, -37, -73, -70, -77,  -3, -15, -40, -41,  44;
/M: SY='T';  M=  -9,-103, -11,  -3, -55,  -9, -60, -66, -30, -57, -41, -17,  58,  21, -23,  33,  60, -67, -47, -44;
/M: SY='Y';  M= -58,  29, -23, -38,  29, -92,   7, -46,  10, -65, -22,   0, -36,  -9,  62, -30, -54, -41,  56,  66;
/M: SY='R';  M= -35, -75, -52, -89, -51, -87, -46,  11, -45,  -1, -25, -70,   3, -50,  97, -32, -35, -25, -22, -69;
/M: SY='G';  M= -36, -78, -52, -39, -73,  95, -76,-117, -73,-105, -85, -24, -34, -31, -32,   4, -53, -96,-107, -88;
/M: SY='D';  M= -12, -75,  99,   1, -70, -67,  13, -93, -38, -63, -35,  25, -59,  10, -53, -13, -50, -77,-123, -74;
/M: SY='L';  M= -73, -79, -93,-108, -56,-117, -77,  21,-108,  80,   2,-112, -92, -86, -86,-105, -52,  30,-105, -86;
/M: SY='E';  M=  -5,-105, -19,  47, -78, -68, -24, -21,   4, -48, -36, -29, -97,  41,  29,  18,  21,  12,-110, -47;
/M: SY='I';  M= -74,-103,-116,-111, -27, -84,-112,  79,-108,  21,   2,-109,-109,-106,-110, -75, -88,  62,-108, -76;
/M: SY='T';  M= -31,-105,  28,  27,  -7, -77,  22, -44,  -9, -41, -46, -19, -99, -14,  -3,  13,  45,  -8,  44,  35;
/M: SY='L';  M= -83,-101,-116,-109, -59,-100,-101,  13,-109,  89,  -7,-114,-114,-103,-107,-108, -82, -22,-103, -69;
/M: SY='T';  M= -77, -55, -79,  -8, -34, -99, -49,  57, -16, -32, -32, -66,-100, -12, -12, -41,  66,  35,-109, -15;
/M: SY='S';  M=  16,   9, -54, -90,-106, -29, -56, -84, -90,-107, -75, -61, -56, -83, -71, 102, -21, -96,-114, -99;
/M: SY='P';  M= -79,-123, -87, -79,-117, -75,-101,-105, -94, -98,-102,-104, 129, -61, -89, -83, -91,-101,-111,-114;
/M: SY='S';  M=  12, -76,  33, -20, -45, -30,  -1,-100, -27, -57,  33,  13, -98,  -1, -27,  72,  -7, -85,-112, -36;
/M: SY='G';  M= -71,-107, -52, -93,-113, 100, -99,-119, -45, -99,-105,  18,-100, -96, -65, -48, -74,-100,-107, -83;
/M: SY='T';  M= -42, -97, -68, -41, -83, -72, -41, -11,  -5, -70,  -7, -60, -94,  -8, -18,  -9, 101, -11, -74, -77;
/I:         I=-20; MI=0; MD=-51; IM=0; DM=-51;
/M: SY='R';  M= -20, -43, -56,  19, -86, -88, -27, -21,  21, -51, -66, -28, -31,  12,  54,   0,  36,  26, -22, -35;
/M: SY='S';  M= -33, -56, -95, -95, -22, -74, -26,  -3, -78, -63, -70, -68,-100, -71, -66,  87,   2,  28,  -7,  38;
/M: SY='T';  M= -50, -62, -37,   4, -93,-105,  -5,  13, -23,   4,  20,  -1, -13,  39,   5, -58,  42,  37, -41, -35;
/M: SY='L';  M= -86,-101,-116,-108, -67,-117,-102,  30, -95,  83,  16,-113, -90,-102, -90,-107, -83,   8,-104, -86;
/M: SY='L';  M=  13, -79, -62, -89, -20, -22,  55, -29,   9,  56,  35, -43, -65,  -2, -58, -44, -55, -12, -40, -55;
/M: SY='N';  M=  15,-103,  32,  -8, -40, -14,   0, -82, -45, -57, -78,  40,  36,  -8, -19,  35,  25, -41,-111, -13;
/M: SY='R';  M=  -6, -63, -18, -12, -32, -22,  -1, -43,   0, -47, -49,   2,  51,  13,  57,   3,   1, -29, -44, -16;
/I:         I=-13; MI=0; MD=-32; IM=0; DM=-32;
/M: SY='R';  M= -28, -44, -25, -25, -91, -10, -53, -77, -34, -59, -71,  11, -46, -15,  94,   9,  12, -65, -71, -96;
/M: SY='P';  M=  -9,  -9, -34, -21, -61,  37, -42, -34,  13, -32, -49, -29,  70, -16,   6,  19, -34, -37,-108, -61;
/M: SY='G';  M= -35, -54, -12, -47,   4,  37,  33, -55,  13,   2, -13,  20, -38,  -4,  16,  -5,  -8, -50, -25,  28;
/M: SY='D';  M= -33,-108, 103, -27, -58,  -6, -59, -68, -77, -89, -87,  11, -47, -33, -38,  13, -35, -51, -83, -57;
/M: SY='D';  M=   7, -21,  24, -11,   1, -21, -21, -12,  16, -38, -22,  21, -52, -14,  12,  21,  23, -31, -61,  10;
/M: SY='S';  M=   5, -78,  48, -14, -25, -25, -18, -40, -47, -51, -66,  31, -71, -16, -42,  63,   7, -16,-112, -28;
/M: SY='N';  M=  10, -44,  28, -38, -58,  -6,  -4, -45,   1, -60, -49,  50,  11,   6,   6,  24,  22, -34,-112, -31;
/I:         I=-19; MI=0; MD=-49; IM=0; DM=-49;
/M: SY='D';  M=   5, -58,  37,  21, -38, -15, -60, -36,   4, -49, -25,  25, -32,  18,  -9,  13,  13, -11, -13,   1;
/M: SY='G';  M= -29, -53, -35, -33, -55,  78, -59, -53, -54, -34, -96, -23, -38, -52, -54, -10,  48, -25, -69,-101;
/M: SY='F';  M= -56,-104, -25, -74,  90, -71, -61,  -6, -71,   9,  -6, -36,-111, -63, -56, -22, -12, -33,  -7,  66;
/M: SY='D';  M= -21, -83,  38,  -3,   3, -40,   5, -53,  15, -46, -37,  26,  -2,  12,   7,  10,  37, -34, -11, -23;
/I:         I=-10; MD=-25;
/M: SY='N';  M= -39, -74,  49, -15, -42,  -2, -16, -44,  -8, -30, -96,  50, -32,   1, -20,   9,   5,  10, -39, -65; D=-10;
/I:         I=-10; MD=-25;
/M: SY='W';  M= -40,-118,  12, -31,  -2, -60, -26, -85, -50, -43, -23,  11, -40,   7, -55, -47, -42, -42, 148,  19; D=-10;
/I:         I=-10; MD=-25;
/M: SY='T';  M=  19, -81,   0, -20, -54, -54, -98, -38, -16, -28, -51, -18,  53, -32, -22,  14,  57, -31, -35, -58; D=-10;
/I:         I=-10; MD=-25;
/M: SY='F';  M= -41, -79,-116, -58,  99, -52, -43, -48, -87, -10,  -4, -70, -54, -97,-110, -43,   7, -13, -89, -43; D=-10;
/I:         I=-10; MD=-25;
/M: SY='M';  M= -45,-109, -27,-105, -61, -34, -78, -48, -84,   0, 101, -14,  14, -64, -88,  15,  10, -26, -54, -98; D=-10;
/I:         I=-10; MD=-25;
/M: SY='S';  M= -17, -83, -73, -64, -35, -36, -75, -72, -87, -61, -59, -57, -50, -67, -87,  72,  61, -52,-121, -72; D=-10;
/I:         I=-10; MD=-25;
/M: SY='V';  M= -51,-110, -64,-113, -27, -87, -45, -11, -93,  -5, -61,  -8, -50, -74, -94, -47,  28,  67,-124, -71; D=-10;
/I:         I=-10; MD=-25;
/M: SY='H';  M=  16, -42, -86, -68, -35, -64,  92,-100,   4, -44, -31, -38, -74,  28,   4, -38, -31, -82, -63, -63; D=-10;
/I:         I=-10; MD=-25;
/M: SY='H';  M= -41,  41, -59, -83,  51, -70,  70, -84, -74, -66, -24,   6, -64, -11, -65,  -2,  10, -81,-113, -10; D=-10;
/I:         I=-10; MI=0; MD=-25; IM=0; DM=-25;
/M: SY='W';  M= -42, -62, -34, -58, -19, -71, -85, -34, -34, -13, -25,   3, -57, -36,  -8,   7, -41, -36, 151,  -7;
/M: SY='G';  M= -18,-107,  24, -51, -79,  89, -50,-116, -87, -84,-105,   6, -37, -58, -74,  -2, -48, -92,-109,-106;
/M: SY='E';  M= -66, -61, -50, 105, -94, -91, -49, -78, -24, -50, -44, -65, -68,  15, -52, -27, -47, -58,-111, -73;
/M: SY='N';  M= -11, -76,  42, -23, -48, -56, -47, -61,  -9, -62, -22,  59,  35,   1,   0,  39,  -6, -50, -83, -51;
/M: SY='P';  M=  50, -77, -82, -81, -80,  -7,-101,  -9, -87, -46, -23, -95,  84, -94, -65,  28, -29, -21,-110,-104;
/M: SY='N';  M=  15,-104, -18,   5, -39, -45, -24, -16,  19, -38, -54,  48, -46,  28,  22,   6,   1,  -8, -62, -28;
/M: SY='G';  M= -64, -78, -96,-108,-114, 104,-103,-105, -88,-117, -79, -56, -84, -99,-109, -74,-100,-115,-106, -80;
/M: SY='T';  M= -50, -76,  24,  27, -88,-101, -70, -13,  -4, -37, -61,  24, -44,  10, -16, -23,  69,   7, -43, -47;
/M: SY='W';  M= -97,-132,-110, -91, -51, -94,-132,-105, -90, -95,-105,-127, -90, -70,-107,-114,-119, -89, 179, -29;
/M: SY='T';  M= -63,-103, -91, -31, -89,-102, -45,  -2,  45, -44, -67, -28, -97,  31,  28, -21,  78, -28, -63, -60;
/M: SY='L';  M= -70,-102, -99, -92, -32,-118,-103,  21, -81,  82, -24, -89, -94,-104, -91, -93, -81,  12,-105, -73;
/M: SY='R';  M= -48,-108, -23,  43, -73, -80,  -7, -14,  28, -49, -44, -36, -99,  30,  50,  -4,  23, -15,   7, -32;
/M: SY='V';  M= -30, -34,-115, -93, -40, -97,-115,  68,-108, -21, -31, -94,-109, -88, -92,-100, -71,  79, -45, -75;
/M: SY='T';  M=  -7, -81, -26,  14, -20, -40,  12,   7,  12, -39, -27, -17, -83,  17,  24,  13,  26,   2, -14,  -4;
/M: SY='D';  M= -45, -56, 107, -61, -60, -65, -73, -98, -75, -70, -70,  41,-100, -87, -76,   0, -35, -75, -57, -53;
/I:         I=-38; MI=0; MD=-97; IM=0; DM=-97;
/M: SY='T';  M= -28, -75,   2, -15, -75, -24,  13, -42,   7, -15,  11,  29, -52,  -5,  -5,  -5,  47,  20, -43, -21;
/M: SY='A';  M=  37,-105,  -2, -14, -37,  36, -20, -84, -28, -71, -51, -15,  11, -19, -47,  31, -35, -13, -28,  14;
/I:         I=-10; MI=0; MD=-24; IM=0; DM=-24;
/M: SY='P';  M=   3,-116, -17, -14, -32, -17, -64, -49, -55, -46, -20,  20,  35, -14,  21,   7, -29, -35, -68, -15; D=-10;
/I:         I=-10; DM=-24;
/M: SY='G';  M=  10, -36, -14,  -7,  -8,  41, -42, -89, -11, -44, -64,  13, -11,  24,  -8,  12,   4, -67,   6, -41; D=-10;
/I:         I=-10; MI=0; MD=-24; IM=0; DM=-24;
/M: SY='D';  M= -26, -43,  75, -14, -75, -21,   6, -50, -18, -52, -60,  50, -71,  21, -48, -23,   8, -26,-120, -31;
/I:         I=-31; MI=0; MD=-79; IM=0; DM=-79;
/M: SY='T';  M= -29, -50, -22, -16, -64, -19,  -6, -19, -11, -38, -23,   6,  21,  -2, -15,  20,  58,   6, -45, -38;
/M: SY='G';  M=   1, -81, -54, -72, -81,  91, -47, -56, -80, -74, -65, -76, -56, -69, -91, -36, -87, -11,-109, -80;
/M: SY='T';  M= -39, -54, -38, -16, -10, -77, -21,  -2,  10, -43, -14, -20, -74,  -2,   5,   7,  66,  -5, -33,  23;
/M: SY='L';  M= -84, -61, -91,-111,  32,-107, -62,  34,-111,  70, -12, -93,-115, -85,-109, -97, -55,   6, -24, -45;
/M: SY='N';  M= -68, -52,  22, -15, -54, -59,   8, -37,  33, -19, -46,  58, -71,   6,   3, -20,  25, -10, -45, -24;
/M: SY='S';  M= -23,-106,  15,   8, -49,  17, -25,-110,  -3, -90, -79,  39,-101,   0,   9,  58, -30, -85, -49, -18;
/M: SY='W';  M= -18, -16,-104, -84,  32, -90, -55, -22,-106, -44, -19,-119, -94, -90, -94, -86, -59, -15, 159, -30;
/M: SY='S';  M= -28, -74, -39,   6, -62, -15, -46, -62,  19, -82, -84, -29, -61,  30,   5,  58,  42, -42, -36, -71;
/M: SY='L';  M= -95,-105, -97, -73, -20,-107, -77,  35,-110,  76,  31, -68,-115, -84, -94, -81, -81, -16,-106, -88;
/M: SY='T';  M= -47, -56, -17,   5, -65, -42,  -8,  10,  -6, -52, -23,   4,-102,   6,  31,   0,  52,  10,-115, -58;
/M: SY='F';  M= -39,-105, -99, -93,  62, -85, -75,  30,-110,  52, -12, -81, -75, -60, -91, -97, -57,  23, -98, -37;
/I:         I=-28; MI=0; MD=-70; IM=0; DM=-70;
/M: SY='Y';  M= -50, -39, -69, -37,  35, -72,  56, -15, -74, -24, -56, -46, -31, -35, -30, -45, -32, -33,  60,  78;
/M: SY='G';  M= -51, -87, -62, -66,-123,  86,-112,-111, -56, -94, -91, -38, -82, -65, -79, -49, -67, -67,-117, -68;
/M: SY='T';  M= -61, -40, -16,  19, -82, -76,  33, -72, -63, -79, -83, -15, -60, -57, -29,   9,  70, -35,-128, -41;
/M: SY='S';  M=  14, -26,  -2,  -9, -39, -43, -40, -79,  -2, -74, -58, -41, -18,  14, -39,  21,  -1, -28, -49, -62;
/M: SY='E';  M= -11, -57,  -2,  22, -75, -43, -62,   1, -20, -66,  -9, -36,   3, -14, -31,   0,   5, -40, -45, -71;
/M: SY='D';  M= -18,-123,  35, -21, -64, -38,   2, -44, -17, -74, -11,   7,  24,  -2, -37, -15,  -6, -71, -95, -55;
/I:         E1=0; IE=-380; DE=-380;

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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.

Total number of hits	55 in 55 different sequences
Number of true positive hits	55 in 55 different sequences
Number of 'unknown' hits	0
Number of false positive hits	0
Number of false negative sequences	0
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	100.00 %
Recall (true positives / (true positives + false negatives))	100.00 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info]	1
Matrix type [info]	protein_domain
Scaling database [info]	reversed
Author [info]	CJA_Sigrist
Feature key [info]	DOMAIN
Feature description [info]	P/Homo B
Version [info]	4

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences

55 sequences

AEX5_CAEEL  (P91863), API_ACHLY   (P15636), APX_STRGG   (P80561),

ASPA_AERSA  (P31339), ASP_AERSO   (Q9L5A4), BLI4_CAEEL  (P51559), 
BLI_ONCVO   (A0A044RE18), BPRV_DICNO  (P42779), BPRX_DICNO  (P42780), 
FKPC1_CAEEL (O17798), FUR11_DROME (P26016), FUR1C_DROME (P30430), 
FUR2_DROME  (P30432), FURI1_XENLA (P29119), FURIN_BOVIN (Q28193), 
FURIN_HUMAN (P09958), FURIN_MOUSE (P23188), FURIN_RAT   (P23377), 
KEX1A_KLULA (P09231), KEX2_CANAW  (O13359), KEX2_YEAST  (P13134), 
KRP1_SCHPO  (Q09175), LIE1_STREX  (P81715), NEC1_BOVIN  (Q9GLR1), 
NEC1_HUMAN  (P29120), NEC1_MOUSE  (P63239), NEC1_MUSCO  (P63240), 
NEC1_RAT(P28840), NEC2_BOVIN  (Q9GLR0), NEC2_CAEEL  (G5ECN9), 
NEC2_DROME  (Q9VBC7), NEC2_HUMAN  (P16519), NEC2_MOUSE  (P21661), 
NEC2_PIG(Q03333), NEC2_PONAB  (Q5REC2), NEC2_RAT(P28841), 
NECA_HYDVU  (P29146), NECB_HYDVU  (P29145), PCSK4_HUMAN (Q6UW60), 
PCSK4_MOUSE (P29121), PCSK4_RAT   (Q78EH2), PCSK5_BRACL (Q9NJ15), 
PCSK5_HUMAN (Q92824), PCSK5_MOUSE (Q04592), PCSK5_RAT   (P41413), 
PCSK6_HUMAN (P29122), PCSK6_RAT   (Q63415), PCSK7_HUMAN (Q16549), 
PCSK7_MOUSE (Q61139), PCSK7_RAT   (Q62849), PRCA_NOSS1  (Q59149), 
PRCA_TRIV2  (P23916), TAMP_STRMB  (P83543), VG47_ICHVA  (Q00139), 
XPR6_YARLI  (P42781)

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Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits:
[Clustal format, color, condensed view] [Clustal format, color]
[Clustal format, plain text] [Fasta format]
Retrieve the sequence logo from the alignment

PDB
[Detailed view]

45 PDB

1OT5; 1P8J; 1R64; 2ID4; 3HJR; 3WQB; 4OMC; 4OMD; 4RYD; 4Z2A; 5JMO; 5JXG;
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