PROSITE entry PS51294

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General information about the entry

PURL [info]	https://purl.expasy.org/prosite/signature/PS51294
Entry name [info]	HTH_MYB
Accession [info]	PS51294
Entry type [info]	MATRIX
Date [info]	01-FEB-2007 CREATED; 01-OCT-2013 DATA UPDATE; 29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info]	PDOC00037
Associated ProRule [info]	PRU00625

Name and characterization of the entry

Description [info]

Myb-type HTH DNA-binding domain profile.

Matrix / Profile [info]

/GENERAL_SPEC: ALPHABET='ACDEFGHIKLMNPQRSTVWY'; LENGTH=59; LOG_BASE=1.000693; P0=0.9972;
/DISJOINT: DEFINITION=PROTECT; N1=1; N2=59;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.9855862; R2=0.0002610; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=23044; N_SCORE=9.0; MODE=1; TEXT='R';
/CUT_OFF: LEVEL=-1; SCORE=15381; N_SCORE=7.0; MODE=1; TEXT='RR';
/DEFAULT: B1=*; E1=*; MM=*; II=*;

...

                A     C     D     E     F     G     H     I     K     L     M     N     P     Q     R     S     T     V     W     Y
/I:         B1=-8455; E0=*; BM=-29; BD=-5668;
/M: SY='M';  M= -803,-4369, 1432,-1076,-4690, -510, 1231,-1419, 1304,-1902, 1554, 1436,-3964,-2070, 1445, -193,  387,-3991,-4553,-3870; M0=-1042;
/I:         MM=-1; MI=-10804; MD=-11846; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='P';  M=-1523,-4398, -470,  306,-1063,-3901, -122,-1448, 1177,-4414,  -82, -266, 3112,  330, -307, -744,-2866,-1516,-4582,-3899; M0=-1297;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='D';  M= -888,-4398, 1551,  344, -216, -367,  -75, -222,  451,-4414, -560, 1392,-1086,-2100,  669,  852,  401,-1516,-4582,-3899; M0=-722;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='I';  M=-1740,  236,-5143,-1660, -910,-4682,  839, 1794, 1470, 1459,-2272,-4196,-4736,-1136,  612,-3749,-1317,  812,-3523,-3171; M0=-1448;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='K';  M=-1330,-4399,-1843,-3029,-4720,-1955,  -42, -984, 3484,-1153,-3488, 1113,-1391,  227, 2876, -808, -639,  186,-4582,-3900; M0=-887;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='K';  M=-3552,-4909,-2041,-3342,-5314, -208, 1184,-1489, 3327,-4889,-4012,-3101,-4534,-2534, 3134,-1671, -472,-4583,-4987,-4424; M0=-2241;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='G';  M= -158, 1019,-1079, -561,-4654, 2779,-2575,-4390,-2163,-2265,-3449,-2557,-1262,  455,  415, -401,   -2, -307,-4550,-3880; M0=-1186;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='P';  M=  690,  -64, -403,-1068,-1188,-3901, -109,-4469, 1484, -922,-3488,  346, 1821, -136,  556,  485,  115,-1649,-4582,-3899; M0=-811;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='W';  M=-6644,-5936,-8656,-8267, 1749,-8524,-5933,-1490,-8033, -710, -183,-7842,-7588,-6661,-7421,-7897,-6459,-4410, 5921,-4158; M0=-5531;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='T';  M=-1633,-4801,-1010, -978,-5117,-4163,-2928,-4874, -368,-1374,-3921, -859,-4327,-2486,-3101, 1595, 3290,-4427,-5002,-4300; M0=-2098;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='E';  M=  -32,-4399,  416, 1925,-4720,-3900, -201,-1565,  967,-2129,-3488, -768, 1713,  965,   -6,-1552,-1152, -520,  400,-3900; M0=-955;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='E';  M= -504,-5203, 1073, 3336,-5501,-1832,-3205,-5280, -754,-5211,-4321,-2968,-4576,  131,-3480,-1577, -162,-4817,-5383,-4641; M0=-2404;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='E';  M=-5356,-7391,  197, 3722, -866,-5073,-4511,-7398,-4967, -891,-6690,-3655,-5668,-1215,-5976,-4953,-5460,-6916,-7263,-6119; M0=-3940;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='D';  M=-1712,-5059, 3387, 1414,-5361,-4281, 1975,-5132,-2777,-5067,-4170,-2903,-4481,  -44,-1032, -842,-3485,-1167,-5237,-4511; M0=-2399;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='E';  M=  281,-4399,  487, 2293,-4720,-3900, -319,-1529,-1011, -746,-3488,  697,-3994, 1797, 1061,-1492,-1373,-1680,-4583,-3900; M0=-1166;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='R';  M=  -39,  223,-4631, -724, -690,-4579,-3396,  981, 1077, 1370, -694,  320,-4640,  -55, 1544,-3619,-1220, -533,  478,-3230; M0=-1077;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='L';  M=-7152,-5537,-8631,-8113, 1173,-8505,-7363, 1679,-7977, 2716,-2719,-8218,-7559,-6817,-7532,-7926,-6027,  679,-5830,-6021; M0=-4965;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='I';  M=-3194,-1190,-5502, -728, -764,-1735,-3607, 1989,  600,  998,  745,-4371,-4788,-4102, 1357,-1863,-3135, 1358,-3483, -391; M0=-1381;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='E';  M=  519,   15,  455, 1782,-4721,-3900,  725, -575, 1604,-4416,-3489, -292,-3993, 1682,  480, -690,-1152,-4022,-4583,-3900; M0=-1378;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='A';  M= 2006,   75,-5412,-1760,-1048,  474,-1931,-2531,-4407, 1690, -353,-1213,-4776, -313,-4251,-3804,-1239,  381,-3492,  177; M0=-1438;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='V';  M= -302,-3055,-5575,-4941, -862,-4781, 2387,  770,-4537, -388,-2252,-4426,-4829, -160,-4338,-3867,-3171, 3054,-3509, -635; M0=-2302;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='K';  M= 1266,-4400,  807,  918,-4721, -872,  240,-1605, 1352,-2892,-3489, -997,-3993, -278, 1268,  599, -473,-1650,-4583,-3900; M0=-951;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='K';  M=-1463,-4394,-1211, 1138,-4713,-1634, 1076, -244, 2189,  598,  618,-1370,-3995,  864, -498, -392,-1822, -693,-4579,-3898; M0=-881;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='H';  M=-3201,  179,-5520,-4886,  708,-4745, 3167,-2524, -870, 1136,  250,  788,-4796,-4114,-1336,-3829,-3142, -509,  329, 2965; M0=-1976;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='G';  M=-5556,-6169,-5808,-4898,-7321, 3597, -136,-6597, -231,-6203,-5565,-4763,  258,-3639, -912,-5458,-5312,-6324,-6002,-5952; M0=-4074;
/I:         MM=-660; MI=-10837; MD=-1448; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='P';  M=  663,-3735,  162, 1173, -512, -316,-2015,-3738,  335,-3733,  317,-2003, 2022,-1569,-2112,-2262, 1503, -216,-3943,-3286; M0=-963;
/I:         MM=-99; MI=-10179; MD=-3940; IM=-894; II=-1115; DM=-41; DD=-5156;
/M: SY='N';  M=-2875,-4343,-1991,-2175,-4662, 1311,-2507,-1659, 1381,-4358,-3432, 1972,   85, 1348, 1541,-2756, -423, -757,-4527, -629; M0=-1261;
/I:         MM=-1; MI=-10776; MD=-11818; IM=-894; II=-1115; DM=-249; DD=-2656;
/M: SY='N';  M=-1414, 1046,  525,-1114,-4721,-3901, 1448,-4472, 1901,-4416,-3489, 2029,-3994, 1179, 2094,  205, -375,-4022,-4583,-3901; M0=-1627;
/I:         MM=-6001; MI=-3768; MD=-135; IM=-49; II=-4907; DM=-701; DD=-1378;
/M: SY='A';  M= 2883,-1124,-2904,-2923,-3168,-1435,-2528,-2639,-2772,-3081,-2297,-1941,-2179,-2490,-2742, -785, 2139,-1872,-3460,-3238; M0=-1722;
/I:         MM=-2516; MI=-283; MD=-8394; IM=-49; II=-4907; DM=-17; DD=-6406;
/M: SY='W';  M=-7719,-6735,-8039,-8396,-4231,-7565,-4658,-7082,-8088,-6390,-6474,-6924, 1047,-7069,-7504,-7447,-7702,-7184, 6191, -238; M0=-6407;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='S';  M= 1355,-4397, -779,-1529,-1188,-3901, -227,-4466, 1831,-2162,-3486,-2537,-3994, -534, 1754, 1538, 1111,-1765,-4581,-3899; M0=-1225;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='K';  M=-1543,-4398,  212,  325,-1137,-1815, -160, -531, 2019,  514, -331,  419,-3994,  158,  847,  330, -453,-3042,-4581,-3899; M0=-714;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='I';  M=-5137,-4613,-7831,-7524,-5187,-7711,-7723, 3657,-7510,-2009,-3905,-7359,-7409,-7443,-7685,-7107,-5127, 1806,-6978, -807; M0=-4984;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='A';  M= 2775,   79,-3185,-1135,-4030, -314,-2806,-3658, -718,  -71,-3046,-2879,   25,-2459,-1158,  720,-2954,-1469,-4214,-3675; M0=-1281;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='K';  M=   24,-4399,  202,  898,-1512,-1774,   94, -641, 1709, -717, -342,  365,-1321,  576, 1138, -617,  412,-4021,-4583,-3900; M0=-629;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='H';  M= -817,-4373,-1133,  672, -433,-1859, 2544, -215,  669,  208, -632,  404,-4001,  631,  819,-1381,-1035, -828,-4563, 1285; M0=-550;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='M';  M= -511,-3028,-5548,-4912,  788,-4750,-3622,   82,-4507, 1823, 2151,-4396,-4800,-4130,-4307, -478, -509, 1698,-3487,  841; M0=-1905;
/I:         MM=-119; MI=-10837; MD=-3672; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='P';  M= -644,-4293, -967, -406, -487, 1521,-2455,-4363,  982,-4308,  -34, -343, 2457, 1227,-1813,-1257,-2761, -558,-4476,-3794; M0=-1166;
/I:         MM=-2724; MI=-4995; MD=-291; IM=-990; II=-1010; DM=-2595; DD=-261;
/M: SY='V';  M=  322,-1137,-3377,-2814, 2071,-2612,-1758, -595,-2474,-1079, -452,-2346, 1075,-2146,-2368,-1743,  750, 2299,-1732,-1383; M0=-1039;
/I:         MM=-7; MI=-8269; MD=-9311; IM=-894; II=-1115; DM=-2994; DD=-194;
/M: SY='D';  M=-1456,-1838, 1552,-1561,-1866,  111, 1111,  180,-1422, 1277,-1016,  509,-2778,-1302,-1750, -205,-1396, 1049,-2232,-1795; M0=-548;
/I:         MM=-5; MI=-8887; MD=-9929; IM=-894; II=-1115; DM=-21; DD=-6119;
/M: SY='G';  M=-1500,  979,-1045,-2229,-4722, 2494, 1077,-4472, -400,-4417,-3491, 1638, -440,-2103,  623, -667,  748,-4023,-4585,-3903; M0=-1516;
/I:         MM=-28; MI=-10837; MD=-5738; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='R';  M=-5767,-6267,-7086,-5085,-7250,-6177,  899,-6448,  921, -851,-5399,-4842,-6056,-3473, 3877,-5634,-5348,-1493,-5817,-5809; M0=-3987;
/I:         MM=-1; MI=-10810; MD=-11852; IM=-894; II=-1115; DM=-385; DD=-2093;
/M: SY='T';  M=-1575,  990,-5486,-4856,-2998,-4736,-3615,  -84,-4465,-1397,  630,  688,-1126,-4100,-4288, 1114, 3164,-1362,-3500,-3157; M0=-1995;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='D';  M=  797,-4398, 2260, -337,-4712, 1473,-2578,-1711,-2163,-4412,-3491,-2553, 1529,-2121,   68, -255,-1041,-4017,-4587, -209; M0=-1313;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='K';  M= -367,-4394,  141, -359,-4713,-1692, -263,  -12, 1949,-1273, -320, 1938,-3995,  161, -978, -695, -421,  293,-4579,  109; M0=-705;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='Q';  M=  234,-4405,  587, -553,-4727,-3904,  662,-4477, -822,-4421,  532,  369,-3998, 3458,-1017,  851,-2871,-4028,-4589,-3906; M0=-1854;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='C';  M=-1834, 4977,-7480,-7086,-4931,-7083,-6681, 1530,-6939,  206,-3737,-6781,-1432,-6760,-6966,-6363,-4840, 1156,-6278,-5845; M0=-4065;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='R';  M=  274,-4151,-3524,-2925,-1028,-1702,-2984,-3921, 2111, -313,-3300, -973,-4445,-2633, 3042,-3338,-1100,-3687,  510,-3923; M0=-1729;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='N';  M= -709,-4399, 1322, 1207,-1196,-3900,   94,-4471,  503, -518,-3488, 1787,-3993,  958, -230, 1520,-2866,-1603,-4583, -769; M0=-1019;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='R';  M=-6820,-6363,-7604,-6641,-1849,-7159, 3669,-6390, 1119,-5760,-5669,-5794,-7025,-5008, 3497,-6504,-6523,-6455,  682,  228; M0=-4749;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='W';  M=  754,-4599,-6856,-6483,-1318,-6260,-3927,-4028,-6074,  859, -243,-5585,-6238,-5436,-5764,-5387,-1273,-4072, 6721, -439; M0=-3714;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='H';  M=-2946, -155,-2872,-1078,-1113,-3951, 2445,  -48, 1291, -753,  550, 1391,-4042, 2171, 1108, -758, -539,-3813,-4460, -206; M0=-1066;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='N';  M=-1420,-4399,  511, -373,-4720, -784,-2559, -599, 1420,-4415,-3489, 2297,-3994,   -9, 1048,  211,  968,  229,-4583,-3900; M0=-1092;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='Y';  M= -841,  186,-5246,-1495,  506,-4699, 2262,-1004,-1753,  817,  683,-1332,-4752,  464, -537,-2108,  183,  538,-1308, 3090; M0=-1071;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='L';  M= -244,-3027,-5498,-4865,  580,-4737,-3606, 1105, -153, 2744, 1751,-1287,-4788,-1141, 1195,-3820,-3135,  331,-4484, -544; M0=-1617;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='N';  M= -833,-4400, 1281,-1038,-4721,-1700, 1027, -705, 1630,-2278,-3489, 1700,-1239, -620, 1570,  652,-2866,-1728,-4583,-3900; M0=-1000;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='P';  M=-1560,-4392, -254,-2230,  355,-3903,  702,-4457, 1218,-1360,-3482, -999, 2525, -774, 1913,-1353,  271,-4012,  524,-3897; M0=-1291;
/I:         MM=-1; MI=-10837; MD=-11879; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='K';  M=-1092,-4398,  170,   66, -909,  564,-2559,-1714, 2025, -115,-3487, -217,-3994, 1486,  175,  371,-1275, -959,-4581,-3899; M0=-700;
/I:         MM=-1; MI=-10810; MD=-11852; IM=-894; II=-1115; DM=-701; DD=-1378;
/M: SY='I';  M=  413,  206,-1186,   13,-3997,-4056, -328, 1574,  691,  750, -287,-4318,-4142, 1001,-1222,  128,-1122,  602,-4175,-1541; M0=-753;
/I:         B0=*; E1=-1000;

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Post-processing [info]

COMPETES_HIT_WITH

PS50090(4); PS51293

Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.

Total number of hits	562 in 343 different sequences
Number of true positive hits	557 in 338 different sequences
Number of 'unknown' hits	0
Number of false positive hits	5 in 5 different sequences
Number of false negative sequences	17
Number of 'partial' sequences	0

Precision (true positives / (true positives + false positives))	99.11 %
Recall (true positives / (true positives + false negatives))	97.04 %

Comments [info]

Taxonomic range [info]	Eukaryotes, Prokaryotes (Bacteria), Eukaryotic viruses
Maximum number of repetitions [info]	3
Matrix type [info]	protein_domain
Scaling database [info]	window20
Author [info]	PS_Langendijk_Genevaux
Feature key [info]	DOMAIN
Feature description [info]	HTH myb-type
Version [info]	4

Cross-references [info]

UniProtKB/Swiss-Prot True positive sequences	338 sequences APL_ARATH (Q9SAK5), APRR2_ARATH (Q6LA43), ARR10_ARATH (O49397), » more Retrieve an alignment of UniProtKB/Swiss-Prot true positive hits: [Clustal format, color, condensed view] [Clustal format, color] [Clustal format, plain text] [Fasta format] Retrieve the sequence logo from the alignment
UniProtKB/Swiss-Prot False negative sequences	17 sequences APRR4_ARATH (Q9FJ16), ARR11_ARATH (Q9FXD6), ARR13_ARATH (Q9ZVD3), » more
UniProtKB/Swiss-Prot False positive sequences	5 sequences DNJC2_MOUSE (P54103), DNJC2_RAT (Q7TQ20), EAF1_CRYNB (P0CO99), » more
PDB [Detailed view]	122 PDB 1A5J; 1BA5; 1GUU; 1GV2; 1GV5; 1GVD; 1H88; 1H89; 1H8A; 1IDY; 1IDZ; 1IGN; » more