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PROSITE entry PS50238


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50238
Entry name [info] RHOGAP
Accession [info] PS50238
Entry type [info] MATRIX
Date [info] 01-JAN-2003 CREATED;
01-OCT-2013 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC50238
Associated ProRule [info] PRU00172

Name and characterization of the entry

Description [info] Rho GTPase-activating proteins domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=188;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=183;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=2.5570621; R2=0.0194412; TEXT='NScore';
/CUT_OFF: LEVEL=0; SCORE=306; N_SCORE=8.5000; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=203; N_SCORE=6.5000; MODE=1; TEXT='?';
/DEFAULT: M0=-8; D=-40; I=-40; B1=-500; E1=-500; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 277 in 277 different sequences
Number of true positive hits 277 in 277 different sequences
Number of 'unknown' hits 0
Number of false positive hits 0
Number of false negative sequences 4
Number of 'partial' sequences 0
Precision (true positives / (true positives + false positives)) 100.00 %
Recall (true positives / (true positives + false negatives)) 98.58 %

Comments [info]

Taxonomic range [info] Eukaryotes
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] N_Hulo
Feature key [info] DOMAIN
Feature description [info] Rho-GAP
Version [info] 3

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
277 sequences

3BP1_HUMAN  (Q9Y3L3), 3BP1_MOUSE  (P55194), 3BP1_RAT(D3ZFJ3), 
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UniProtKB/Swiss-Prot
False negative sequences
4 sequences

DEP1A_DANRE (Q803Q4), DEP1A_HUMAN (Q5TB30), DEP1A_MOUSE (Q8CIG0), 
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PDB
[Detailed view]
63 PDB

1AM4; 1F7C; 1GRN; 1OW3; 1PBW; 1RGP; 1TX4; 1XA6; 2EE4; 2EE5; 2MBG; 2NGR;
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