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PROSITE entry PS50045


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General information about the entry

PURL [info] https://purl.expasy.org/prosite/signature/PS50045
Entry name [info] SIGMA54_INTERACT_4
Accession [info] PS50045
Entry type [info] MATRIX
Date [info] 01-NOV-1997 CREATED;
10-MAY-2017 DATA UPDATE;
29-MAY-2024 INFO UPDATE.
PROSITE Doc. [info] PDOC00579
Associated ProRule [info] PRU00193

Name and characterization of the entry

Description [info] Sigma-54 interaction domain profile.
Matrix / Profile [info]
/GENERAL_SPEC: ALPHABET='ABCDEFGHIKLMNPQRSTVWYZ'; LENGTH=230;
/DISJOINT: DEFINITION=PROTECT; N1=6; N2=225;
/NORMALIZATION: MODE=1; FUNCTION=LINEAR; R1=0.4518000; R2=0.0129291; TEXT='NScore';
/NORMALIZATION: MODE=-1; FUNCTION=LINEAR; R1=570.4483032; R2=21.7931042; PRIORITY=1; TEXT='Heuristic 0.5%';
/CUT_OFF: LEVEL=0; SCORE=623; H_SCORE=14148; N_SCORE=8.5; MODE=1; TEXT='!';
/CUT_OFF: LEVEL=-1; SCORE=468; H_SCORE=10770; N_SCORE=6.5; MODE=1; TEXT='?';
/DEFAULT: D=-20; I=-20; B1=-50; E1=-50; MI=-105; MD=-105; IM=-105; DM=-105;
...
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Numerical results [info]

Numerical results for UniProtKB/Swiss-Prot release 2025_01 which contains 572'970 sequence entries.


Total number of hits 166 in 166 different sequences
Number of true positive hits 158 in 158 different sequences
Number of 'unknown' hits 0
Number of false positive hits 8 in 8 different sequences
Number of false negative sequences 0
Number of 'partial' sequences 2
Precision (true positives / (true positives + false positives)) 95.18 %
Recall (true positives / (true positives + false negatives)) 100.00 %

Comments [info]

Taxonomic range [info] Prokaryotes (Bacteria)
Maximum number of repetitions [info] 1
Matrix type [info] protein_domain
Scaling database [info] reversed
Author [info] K_Hofmann
Feature key [info] DOMAIN
Feature description [info] Sigma-54 factor interaction
Version [info] 5

Cross-references [info]

UniProtKB/Swiss-Prot
True positive sequences
158 sequences

ACOR_BACSU  (O31551), ACOR_CUPNH  (P28614), ALGB_PSEAE  (P23747), 
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UniProtKB/Swiss-Prot
'Partial' sequences
2 sequences

NTRC_VIBAL  (P19905), YFHA_KLEOX  (P21710)

		
UniProtKB/Swiss-Prot
False positive sequences
8 sequences

CLPB_PSEPK  (Q88Q71), DNLJ_BACVZ  (A7Z261), LONB_ARCFU  (O29883), 
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PDB
[Detailed view]
23 PDB

1OJL; 2BJV; 2BJW; 2C96; 2C98; 2C99; 2C9C; 2VII; 4QNM; 4QNR; 4QOS; 5EXP;
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